CAS： 6413-10-1
MF： C8H14O4
|
Trade name |
Fructone (IFF), Jasmaprunat (Symrise) |
InChI:InChI=1/C8H14O4/c1-3-10-7(9)6-8(2)11-4-5-12-8/h3-6H2,1-2H3
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ethyl acetoacetate
ethylene glycol
![(2-methyl-[1,3]dioxolan-2-yl)-acetic acid](/upload/2025/8/ae5f9906-26b5-4fe0-866c-fd75efb38c6a.png)
(2-methyl-[1,3]dioxolan-2-yl)-acetic acid
fructone
| Conditions | Yield |
|---|---|
|
β-1 zeolite;
In
toluene;
at 145.85 ℃;
for 1h;
Further Variations:;
Catalysts;
Temperatures;
Pressures;
Product distribution;
|
91% 4% |
ethyl acetoacetate
ethylene glycol
fructone
| Conditions | Yield |
|---|---|
|
With
montmorillonite K-10;
In
benzene;
for 6h;
Heating;
|
98% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 48h;
Reflux;
|
98.6% |
|
With
Amberlyst15;
In
cyclohexane;
Reagent/catalyst;
Solvent;
Reflux;
|
97% |
|
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at 25 ℃;
for 48h;
|
96% |
|
USY-3 zeolite;
In
toluene;
at 145.85 ℃;
for 1h;
|
96% |
|
With
toluene-4-sulfonic acid;
|
96% |
|
With
chitosan immobilized with 3-(3-vinylimidazolyl)propane-1-sulfonate and 12-phosphotungstic acid;
In
cyclohexane;
at 80 ℃;
for 2h;
Time;
Reflux;
Dean-Stark;
|
96.2% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 17h;
Heating;
|
95% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 24h;
Heating;
|
93% |
|
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
|
92% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 8h;
Heating;
|
91% |
|
With
toluene-4-sulfonic acid;
In
toluene;
Reflux;
|
91% |
|
With
polyaniline-sulfate salt;
In
toluene;
for 1.5h;
Heating;
|
90% |
|
With
toluene-4-sulfonic acid;
|
90% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 8h;
Heating;
|
90% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 5h;
Heating;
|
90% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 20h;
Reflux;
|
88% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 24h;
Dean-Stark;
Reflux;
|
87% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 8h;
Heating;
|
86% |
|
With
toluene-4-sulfonic acid;
In
toluene;
for 4h;
Reflux;
|
83% |
|
With
toluene-4-sulfonic acid;
In
toluene;
for 12h;
Heating;
|
80% |
|
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
|
75% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 20h;
Heating;
|
73% |
|
With
toluene-4-sulfonic acid;
In
benzene;
for 24h;
Heating;
|
70% |
|
With
N,N,N-triethyl-N-butanesulfonic acid ammonium hydrogen sulfate;
at 79.99 ℃;
for 2h;
Temperature;
Concentration;
Reagent/catalyst;
Time;
|
61.6% |
|
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
|
58% |
|
With
toluene-4-sulfonic acid;
In
toluene;
for 5h;
Dean-Stark;
Heating;
|
54% |
|
|
|
|
With
toluene-4-sulfonic acid;
|
|
|
With
toluene-4-sulfonic acid;
In
benzene;
|
|
|
|
|
|
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
|
|
|
With
carbon-based acid prepared by carbonization of furaldehyde and 2-hydroxyethylsulfonic acid;
In
cyclohexane;
for 2.5h;
Reflux;
|
|
|
With
tin(II) hydroxide chloride;
In
neat (no solvent);
at 100 ℃;
for 2h;
under 760.051 Torr;
Reagent/catalyst;
|
|
|
With
toluene-4-sulfonic acid;
In
toluene;
|
|
|
With
toluene-4-sulfonic acid;
In
benzene;
for 20h;
Reflux;
|
|
|
With
toluene-4-sulfonic acid;
In
toluene;
for 2h;
Dean-Stark;
Reflux;
|
|
|
With
toluene-4-sulfonic acid;
In
benzene;
for 48h;
Reflux;
|
|
|
With
acidic PO3H-functionalized cellulose;
In
neat (no solvent);
at 120 ℃;
for 6h;
Reagent/catalyst;
Solvent;
chemoselective reaction;
Green chemistry;
|
ethyl acetoacetate
ethylene glycol
2-(2-methyl-1,3-dioxolan-2-yl)ethanol
(2-methyl-[1,3]dioxolan-2-yl)-acetic acid
3,3-ethylenedioxybutanal
ethyl acetoacetate